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Both residues are not required for MDSA or EA binding, as indicated by the fact that the IC 50 values of the N92A, N92Q, and R128A mutants were not markedly increased, indicating that these mutants remained susceptible to MDSA or EA inhibition (Table 1)

10.3390/ijms20153673 72 LiuX.ZhangZ.RuanJ.PanY.MagupalliV

Alcoholism and Other Socio-Demographic Risk Factors for Adverse TB-Drug Reactions and Unsuccessful Tuberculosis Treatment - Data From Ten Years' Observation at the Regional Centre of Pulmonology, Bydgoszcz, Poland

97(Pt A), 3645

XuXWangHGuoDManXLiuJLiJet al

So even if you dont smoke, but youre around others that do, you could end up having higher homocysteine levels that impact your health