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PMR: Post-marketing requirement (PMR) trial for dose optimization

The binding of GTP then stimulates adenylyl cyclase, thus increasing intracellular cyclic 3 ,5 -adenosine monophosphate (cAMP)

doi:10.1016/j.phymed.2024.155345 29

CACNA1A modulates ferroptosis through calcium signal in ovarian cancer Previous literature has reported that VGCCs induce ferroptosis by influencing the Fenton reaction, resulting in an overaccumulation of ROS [22]