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MT-II acts as a non-selective agonist at melanocortin receptors (MC1R, MC3R, MC4R, MC5R), with its most extensively studied effect being the stimulation of melanogenesis the biological process by which melanin pigment is produced in skin and hair follicles

8, July 2011, pp

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Further, lipid peroxidation leads to fragmentation of PUFAs and membrane lipid damage, leading to irreversible membrane perforation and ferroptosis through a transmissible osmotic mechanism (Riegman et al