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The results of this model reveal high BACs in mice, along with significant elevations in serum ALT and AST levels, both peaking at 9 h after administration

Molecular targeting of hypoxia in radiotherapy

"I would say that there's a risk there." Ward 10 Coun

Oct 2016;70:143-148

This NBC-Los Angeles news story that aired Wednesday also does a good job summarizing concerns

(1) ROS directly attacks the mitochondria of chondrocytes, causing leakage of the electron transport chain (ETC) and further generating superoxide anion (O ), which forms a vicious cycle, inducing collapse of mitochondrial membrane potential and ATP synthesis disorder