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Toxin elimination

As a control, catalytically inactive mutant PknB-K40M 18 was co-expressed with Mtb -SahH instead of PknB

Bharath S, Hsu M, Kaur D, Rajagopalan S, Andersen JK

Exclusion criteria were applied before enrollment and included the following: individuals under 18 years of age

Although the subjects had different lengths of time since the onset of the symptoms and different House-Brackmann grade points, they all responded almost to the same point after treatment, respectively over a one-month period of time

During the 2 years of the project a novel LC-MS/MS method for the quantification of 27endogenous steroids, including major circulating hormones as well as a wide panel of androgens phase II metabolites, was developed and validated according to WADA guidelines