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Nat Rev Dis Primers 3(1):17018 Bode JG, Ehlting C, Hussinger D (2012) The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis

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Therapeutic strategies targeting the ntfs-mitochondrial axis Based on the regulatory mechanism of the NTFs-mitochondrial axis, developing innovative therapeutic strategies represents a promising yet challenging direction for PD treatment

On the other hand, all exogenous antioxidants support prooxidation chemistry that can also trigger OS by promoting the release of ROS under certain conditions, which is essential to kill neoplastic cells by inducing different cell death pathways to exert chemotherapeutic effects [60, 146, 197,198,199,200, 208, 213, 259]