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Possible beneficial effects of N-acetylcysteine for treatment of triple-negative breast cancer

Makin, S

Zhu H, Wu TC, Chen WQ, Zhou LJ, Wu Y, Zeng L, Pei HP

doi: 10.1186/s12958-016-0205-6 79 Diamanti-KandarakisEChatzigeorgiouAPapageorgiouEKoundourasDKoutsilierisM

To start with, in the process of ferroptosis, Hmox1 is activated, which promotes the increase of LIP and destroys cell homeostatic capacity, thus compromising the integrity of cardiomyocytes (Kakhlon and Cabantchik 2002)