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Description

Compared with free SCU, it prolongs the in vitro release spectrum and blood circulation duration of SCU, increases SCU levels in ischemic brain tissue, and significantly reduces cerebral infarction volume

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Its central melanocortin receptor profile has been the subject of in vitro and ex vivo research examining hypothalamic signaling pathways and neuropeptide receptor pharmacology

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Neuronal survival: The activation of these signaling pathways promotes neuronal survival by enhancing cell survival signals and inhibiting cell death signals

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[DOI] [PMC free article] [PubMed] [Google Scholar] Brusselle G., Germinaro M., Weiss S., Zangrilli J

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Overproduction of ROS can induce cell death via signaling pathways such as autophagy and apoptosis, resulting in oxidative stress

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