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While hypercalcemia involves dysregulation of calcium homeostasis often mediated by parathyroid hormone-related protein and osteoclast activation, it shares with copper dysregulation a common theme of metal ion imbalance in cancer pathophysiology

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In some cases, such as VCL1 (118.70 m/s) and VAP1 (54.52 m/s), Niacin 1 even exceeded the Control values, highlighting a strong restorative or even enhancing effect