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Eur J Med Res 29 , 398 (2024)

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Meanwhile, Lentinula edodes (shiitake) is particularly rich in lentinan, a -glucan with immunomodulatory and anti-cancer properties [105]

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A recent study showed that glucose metabolism was dysregulated and that pyruvate supplementation could prevent neurodegeneration in an animal model of glaucoma 31 , suggesting that ATP production from glycolysis is disrupted, and that other energy fuel pathways, such as -oxidation, may be augmented to compensate for the reduction in energy metabolism