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Upon treatment with ferroptosis inhibitors, a significant reduction in the pathophysiological manifestations was observed in the murine models, concomitant with a substantial increase in overall survival rates [76]

10.1016/j.burns.2020.09.003 Burns

Combined with the reduction in microbial -diversity and stability, we hypothesize that the structural changes in the microbial community may be a primary driver for altering the metabolic output in yaks

Grgoire L, Samadi P, Graham J, Bdard PJ, Bartoszyk GD, Di Paolo T (2009) Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of L-Dopa in parkinsonian monkeys

doi: 10.1016/j.redox.2024.103345 14 PengXSunBTangCShiCXieXWangXet al

thus, drug repurposing represents an alternative and effective strategy, which reduces both development costs and timeliness by using already approved compounds to offer alternative clinical options