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L., Dreher M., Davenport A

These mutations impair DNA binding, resulting in dominant negative effects and possible gain-of-function characteristics, which further augment ROS generation, angiogenesis, and synovial invasion [48]

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Because of this, a growing number of studies suggested that these actions make polyphenols a potential therapeutic approach as an available adjuvant to medical and non-medical treatment to aid in the clinical management of IBD, although the available evidence to support their clinical use is still limited [48]

[DOI] [PubMed] [Google Scholar] Lee BH, Kim YK

S7A, B) and FACS (Fig