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Biochemistry 60 (48), 36763696

Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction

The TLR4-NF-B pathway is also inhibited by SSB2 in LPS-induced microglia, which suppresses the activation of microglia and reduces the levels of IL-1, IL-6, and TNF-, increasing the anti-inflammatory cytokine IL-10 (Wang et al., 2023)

At low concentrations (0.01 nM), MMP1 and MMP2 gene expression increases, facilitating removal of damaged ECM proteins

Unsaturated PUFAs, especially arachidonic acid (AA) and adrenoyl acid (AdA), are prone to react with ROS, leading to lipid peroxidation and inducing cell ferroptosis