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In our study, FOXO4-DRI was found to effectively promote apoptosis in senescent cells by blocking the FOXO4-P53 interaction and facilitating P53 phosphorylation

Anti-BCMA CAR t-cell therapy CT103A in relapsed or refractory AQP4-IgG seropositive neuromyelitis optica spectrum disorders: phase 1 trial interim results

At 48 h after the operation, mice were intravenously injected with LNP@AmB at a dose of 1 mg/kg amphotericin B every day for 5 days and images were obtained with a Lumina III Imaging System (PerkinElmer, USA) at 0 d, 3 d, and 6 d after treatment

Comparable oxidative stress responses have been observed in other bacteria, including Acinetobacter baumannii and Escherichia coli (7, 50)

mansoni TGR IC 50 Values of TGR Inhibitors with 15-Minute Preincubation Assays The gold complexes AF, aurothioglucose, and aurothiomalate, which are efficient inhibitors (i.e., with low K i /IC 50 values) of mammalian TrxR [29,30], were found also to be efficient TGR inhibitors

70.95 1.16 mmHg