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24 Epitalon is a 4-amino acid pluripotent peptide and regulator of the brain, pineal glands, and retina

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Notoginsenoside Ft1 causes vasodilation by activating glucocorticoid receptors ( GR ) and estrogen receptor beta ( ER ) in endothelial cells

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Given the rich lipid content of the nervous system, hemoglobin-derived iron works with lipid peroxidation to induce ferroptosis, which eventually leads to neuronal mitochondrial damage, edema, and apoptosis of neurons and astrocytes