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This systematic review finds substantial evidence that IF can modulate the immune system in non-obese healthy people, obese people, and subjects in other physiological or pathophysiological states and these effects were clinically relevant with cognitive improvement, lipid and metabolism regulation, and inflammatory state remission

Melanocortin Analogues Melanocortin receptor agonists (e.g., melanotan-class compounds) have been associated in research settings with flushing, transient welts, or mild itching

But the gap between the two compounds may narrow in real-world settings where adherence and dose optimization are less consistent

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Sevillano et al., 2021

Bridging multiple disciplines and combining various sources of data necessitate expertise and collaboration between researchers