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Powerful glycemic control with compelling weight loss with Ozempic (semaglutide) injection 1 (semaglutide) injection 1 Ozempic is not indicated for weight loss Ozempic vs Lantus and Ozempic 1 mg vs 2 mg 1 Primary endpoint: change in A1C from baseline SUSTAIN 4: vs study-titrated Lantus 1,5 In insulin-nave adult patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 30 Mean baseline A1C: 26% of insulin patients titrated to goal by Week 30

doi: 10.3389/fimmu.2025.1558414 Received 13 January 2025 Accepted 04 February 2025 Published 21 February 2025 Volume 16 - 2025 Edited by Jin-Yi Wan, Beijing University of Chinese Medicine, China Reviewed by Hui Ye, Peking University, China Ke Xiao, Shandong University, China Weihan Zhao, Shaanxi University of Chinese Medicine, China Updates Copyright 2025 Guan, Cheng, Zhang, Cai, Zhang, Jiang, Wang, Zeng and Jia

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In effect, arsenate uncouples the GAPDH and PGK reactions

FIGURE 7 In summary, PCs participate in T2DM pathophysiology via multiple mechanisms, such as enhancing insulin secretion, safeguarding pancreatic -cells, optimizing mitochondrial function and insulin resistance, and regulating hepatic lipid metabolism