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It's a mechanical problem and an inflammatory one, all rolled into one

10.1016/j.biomaterials.2005.06.042 46 MochidaJ.SakaiD.NakamuraY.WatanabeT.YamamotoY.KatoS

(2021) 53:e13577

Conclusion Here we presented a BBB-targeted nanodrug delivery system coupled with dopamine and ibuprofen

6 Conclusion and perspectives The dynamic regulatory network formed by gut microbiota and the ENS constitutes a central regulator of intestinal homeostasis, with its dysfunction playing a pivotal role in the pathogenesis and progression of DGE