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Third, although protective effects were observed in preclinical models, their applicability to human OA remains uncertain, and well-designed clinical trials are necessary to validate these findings

The suspension was centrifuged at 15,000 g for 20 min at 4C, and the resulting supernatant was used directly as an enzyme source ( SOD (EC 1.15.1.1) activity was determined based on the capacity of the enzyme to inhibit the photoreduction of nitroblue tetrazolium (NBT) ( CAT (EC 1.11.1.6) activity was assayed, according to the method of 1 cm 1 ) as a result of H 2 O 2 degradation

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Glia 70 , 354367 (2022)

This is not a complete list and there are many others. The warning relates to both the unproven effects of these products, but also the risk of infection from possible non-sterile products being injected

IEEE Trans