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The balance between these two effects determines the steady state concentration of GSH

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Finally, the fourth mechanism entails target modification, which can occur through mutations, enzymatic alterations, and replacement 19,64,65

Main text By-products of O 2 metabolism, detoxification mechanisms and the role of oxidative stress Mitochondrial oxidative phosphorylation is the final stage of cellular respiration, following glycolysis, pyruvate oxidation and the citric acid cycle

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Abbreviations , increased