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Figure 3 3.2 Anticancer mechanisms of carotenoids 3.2.1 Pro-oxidant and antioxidant balance Carotenoids are a class of strong antioxidants that scavenge free radicals and reduce DNA damage from oxidative stress, thereby preventing genetic mutations and cancerous lesions ( 3.2.2 Immunomodulatory effect Carotenoids also exert anticancer effects through immunomodulation

Boyce Altered redox biology challenges all cells, with compensatory responses often determining a cells fate

In a recent randomized Phase II trial, a broccoli sprout-derived SFN supplement given to former smokers for 12 months significantly decreased the Ki-67 proliferative index in their bronchial epithelium compared to an increase in the placebo group

Int J Chem Stud 8:23542361 Couto N, Wood J, Barber J (2016) The role of glutathione reductase and related enzymes on cellular redox homoeostasis network

[DOI] [PubMed] [Google Scholar] 7.Kim DH, et al

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