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Dogs may also present in acute crisis, which may reflect a sudden decompensation of occult chronic liver disease

Subsequently, we transformed the normalized matrix to a similarity matrix based on the pairwise Pearsons correlation among the 13,707 genes and then converted the similarity matrix into an adjacency matrix

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To further investigate this interaction, we mutated different amino acids in these linkers, which resulted in significantly reduced disruptions in O-GlcNAc homoeostasis compared to that from wild type OGA (Supplementary Fig