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Without enough of it, fatty acids cant effectively enter the mitochondria, and instead of being burned off, fat can accumulate

The effect of powdered feed on oligodendroglia should also be considered when designing remyelination studies, as a change to powdered control chow from powdered cuprizone diet may not reflect a full return to a healthy mature oligodendrocyte population that is able to remyelinate fully

Liaw A, Wiener M

Alcohol also disrupts sugar metabolism, promoting candida overgrowth that produces excess gas and bloating

2 Mitochondrial GSH import is mediated by SLC25A39

However, other forms such as L-carnitine fumarate and Acetyl-L-carnitine may also be effective, depending on individual needs