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Curcumin inhibits proliferation and invasion of osteosarcoma cells through inactivation of Notch-1 signaling

Concurrently, total brain ferritin levels are decreased despite elevated ferritin deposition in the substantia nigra, where an increased ferritin heavy chain-to-light chain ratio is associated with reduced iron storage stability ( The Fenton reaction, in which ferrous ions catalyze the conversion of H 2 O 2 into highly reactive hydroxyl radicals (OH), initiates lipid peroxidation by abstracting hydrogen from polyunsaturated fatty acids, ultimately driving ferroptotic cell death (Gow et al., 1996)

Kim T, Lawson MA

PMID 9314899

Cheng Peng, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Available from: /pmc/articles/PMC9118284/ 69