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In a recent double-blinded randomized placebo-controlled study, it was shown that endurance performance (i.e., time to exhaustion during a graded exercise test) in active healthy young women was enhanced by 21.17 s (8.5%), along with increased total and lower limb lean mass, by moderately increased testosterone concentrations (to a mean of 4.3 nM, which is 4.8 times higher than the baseline level) for 10 weeks compared to placebo (Hirschberg et al., 2020)

Furthermore, ROS can induce additional loss of membrane potential by activating the mPTP, ultimately triggering cell apoptosis

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BBR can boost the presence of Ruminococcus, Desulfovibrio vulnificus, Lactobacillus , and A