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The Journal of Biological Chemistry

PLGA nanoparticles prepared by nano-emulsion templating using low-energy methods as efficient nanocarriers for drug delivery across the blood-brain barrier

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He went on to conclude that even though the presence of senile plaques and neurofibrillary tangles were observed, the plaques are not the cause of senile dementia, but only an accompanying feature of senile involution of the central nervous system [7]