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The current ongoing trial of Nrf2 activator is shown in Table 5

Singh, Evaluation of oxidative stress before and after control of glycemia and after vitamin E supplementation in diabetic patients, Metabolism

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12 Pathophysiology and signaling pathways involved T2D, usually accompanied by other manifestations of MDS, is a complex metabolic disease with multiple underlying mechanisms not fully understood, while IR and cell dysfunction are two core pathophysiological mechanisms 13,14 (Fig