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5.2 Microbial factors directly modulating -cells: LPS, indoles and BefA SCFAs, particularly butyrate, protect -cells not only by enhancing GLP-1 secretion but also through profound immunomodulatory effects that attenuate islet inflammation

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GSH is exclusively degraded at the extracellular level by cells expressing -glutamyltranspeptidase (GGT), such as those of the hepatobiliary tree and of other organs like the heart, kidney, lungs, pancreas, and seminal vesicles

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Survival with native liver at 5 years ranging from 77 to 97% and event-free survival of 69% has been reported [184, 190,191,192,193,194]

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