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Proc Natl Acad Sci U S A (2001) 98:1084550.10.1073/pnas.191207498 126 PatelJMLiYDZhangJGelbandCHRaizadaMKBlockER

Manna S, Karmakar S, Sen O, Sinha P, Jana S, Jana S

They also support the antioxidant system by enhancing the activity of enzymes such as APX and GR, which mitigate HO-induced membrane damage

The methoxylated flavones are ayanin and 3-o-glucosides, quercetin, rutinosides of kaempferol and isohamnetin [46]

As polyphenols are poorly bioavailable, they accumulate in the colon and are extensively metabolized by the resident gut bacteria, generating polyphenol-derived microbial metabolites