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The dose-dependent activation of the FAK-paxillin pathway has been documented in multiple studies

GSH can be toxic, especially in cases of ascorbate deficiency, and these effects may be demonstrated in, for example, ascorbate deficient guinea pigs given 3.75 mmol/kg daily (1 ,152 mg/kg daily) in three divided doses, whereas in non-ascorbate deficient animals, toxicity was not seen at this dose, but were seen at double this dose

Kadiyala, A., et al

Patent Number: 6,899,870

[DOI] [PubMed] [Google Scholar] 123.Vidovi B., Milovanovi S., Stefanovi A., Kotur-Stevuljevi J., Taki M., Debeljak-Martai J., Pantovi M., orevi B

Dosage form vial5