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This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis

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Astaxanthin, a xanthophyll carotenoid exhibits potential anti-cancer effects by both chemopreventive and chemotherapeutic mechanisms