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Essentially, your kidneys have to work harder, and in people who already have kidney issues, this extra work might speed up kidney function decline

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Many protocols can be conveniently self-administered at home with comprehensive education, ongoing RN guidance, and provider oversight

In further embodiments, the invention encompasses a method of inhibiting NNMT in vitro or in vivo by contacting a cell expressing NNMT with one or more cations of the invention and with one or more cations chosen from Tables 3a and 3b