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Since water can freely move across both the cell membrane and the cell wall, the cell is at risk for an osmotic imbalance, which could put pressure on the relatively weak plasma membrane

There were 75 patients (88% of the original sample) in the intent-to-treat analyses

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The treatment efficacy on pain was evaluated using VAS, Total Symptom Score (TSS), Clinical Global Impression of Change, McGill Pain Questionnaire (MPQ), and the need for rescue analgesics