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found that the abnormal accumulation of double-stranded DNA in the cytoplasm may bind to the cytoplasmic DNA sensor (cGAS), thereby specifically triggering the STING-interferon (IFN) signaling pathway in microglia, promoting the expression and secretion of inflammatory cytokines

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The retina, particularly the macula, is highly susceptible to oxidative stress due to its high metabolic activity and exposure to light (3)

Cataract surgery may also be inadvisable if the patient suffers from other forms of ocular disease, such as age-related macular degeneration, which was reported by some clinicians to worsen after cataract surgery (Casparis 2012)

lipids synthesized and stored in the liver are released into the blood to supply very low-density lipoproteins (VLDL) to other organs or LDs in the form of TGs

Cellular senescence and Alzheimer disease: the egg and the chicken scenario