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He places tobacco in the category of adiaphora , writing, Life and Time are more precious than to have a large Share of them laid out in scrupulous Enquiries, whether smoaking Tobacco, or wearing a Periwig be lawful or no. 47 Isaac Watts, Logick: or, The Right Use of Reason in the Enquiry after Truth, with w Variety of Rules to Guard Against Error, in the Affairs of Religion and Human Life, as well as in the Sciences (London: John Clark, Richard Hett, Emanuel Matthews, and Richard Ford, 1722), 405

Epidemiological studies of tobacco use multivariate analysis to control for any number of factors associated with likelihood of disease: education, age, ethnicity, income, gender, etc

Recent studies have also shown that e-cigarettes are more effective than nicotine replacement medicines in helping people who want to quit smoking

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However, for many smokers, the fear of weight gain looms large, acting as a significant deterrent to giving up cigarettes