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Description

While CBP/p300 is a well-validated direct interaction partner of NRF2 with prominent functions at enhancers, we report that this interaction is not required for NRF2-dependent NSCLC cell growth, indicating that NRF2 can sustain sufficient transcriptional activity in the absence of CBP/p300 coactivation

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PubMed Central, Vincenti, Alessandra, et al

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Importantly, this limitation is not restricted to musculoskeletal models, but reflects a broader challenge within aOoC research, where reconstructing patient specific vascularized niches remains a major biological and engineering frontier

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Nicotinamide adenine dinucleotide (NAD) is comprised of a redox pair of NAD+ (oxidized) and NADH (reduced)

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