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Although the cerebellum is less affected in AD pathology, abnormal copper levels in this region may be associated with impaired motor coordination and cerebellar function in some AD patients (86)

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Based on current clinical guidelines from the WHO and the American Heart Association (AHA), adults should aim for 150300 min of moderate-intensity aerobic exercise or 75150 min of vigorous-intensity aerobic exercise each week, ideally paired with muscle-strengthening activities on two or more days

10.1016/j.jep.2019.112308 73 LuoD.DongX.HuangJ.HuangC.FangG.HuangY