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Statistical significance was determined by ordinary one-way ANOVA with multiple comparisons (no correction)

116 In AVS patients, DVL2, GSK3, -catenin, and SFRP2 are upregulated in the stenotic aorta

S33 Gating strategies

BCAA includes Leu, iLe, and valine, and all three amino acids participate in the citric acid cycle by producing acyl-CoA derivatives via branched-chain amino acid transferase (BCAT), branched-chain -keto acid dehydrogenase (BCKDH), which in a subsequent series of reactions produce acetyl-CoA