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Researchers studying cellular repair pathways, angiogenesis, or connective tissue biology often find that examining both compounds within the same experimental framework yields richer comparative data

One possible side effect is leg cramping (also referred to as a charley horse)

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doi:10.1016/j.ejphar.2015.11.048 Tan SW, Israf Ali DAB, Khaza'ai H, Wong JW, Vidyadaran S

The compound appears to maintain NO homeostasis under conditions of both excess and deficiency upregulating eNOS-derived NO in ischemic models while attenuating iNOS-driven overproduction in inflammatory contexts (Sikiric et al., 2014, Current Pharmaceutical Design 2014