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The end products of lipid peroxidation, such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), are themselves reactive and can further propagate oxidative damage [33]

Finally, the buffer was exchanged to PPS buffer, the concentration measured and the apo-enzyme flash-frozen as described for At LDOX

Metabolic response of humans to ingestion of nicotinic acid and nicotinamide

This raises questions regarding the actual cytosolic NADP redox state and how variable it might be under different conditions or in different organisms