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Although many of the studies in humans reported conflicting results, there was consistent evidence that aspartame increased serum insulin levels in lambs and in several studies in rodents, indicating alterations in insulin sensitivity, including changes to lipid metabolism

The three key treatment strategies for migraine are a personalised management approach addressing lifestyle factors, acute medications and preventive medications

10.1002/med.21396 77 LuoJ.MillsK.le CessieS.NoordamR.van HeemstD

Cell Host Microbe 7 , 500508 (2010)

For those in search of a higher-dose supplement, such as with B12 deficiency, 5000mcg per day can safely be used

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