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[DOI] [PubMed] [Google Scholar] 30.Potential anticancer and antioxidant lauric acid-based hydrazone synthesis and computational study toward the electronic properties

Recently, Bermudez et al, demonstrated that maintaining aspartate import in tumors enables cancer cell proliferation under ETC inhibition and hypoxia

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PT2385 is one of the very few HIF-2 inhibitors investigated in preclinical models of GBM and works by preventing allosteric heterodimerization with HIF-1 when it binds to HIF-2 PAS-B domain (156)