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What Are the Potential Sites of Protein Arylation by N Acetyl p benzoquinone Imine (NAPQI)? Chemical Research in Toxicology NAPQI Wikipedia Acetaminophen metabolism. Acetaminophen is metabolized primarily by sulfation and glucuronidation. However, it can also be oxidized by CYPs to form NAPQI. NAPQI can then interact with cellular macromolecules, resulting in toxicity, or it can be detoxified The molecular mechanisms of acetaminophen induced hepatotoxicity and its potential therapeutic targets PMC Acetaminophen Pathway (toxic doses), Pharmacokinetics Acetaminophen Anesthesia Key
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