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Hum Exp Toxicol 24(3):129135 Dewidar B et al (2019) TGF- in hepatic stellate cell activation and liver fibrogenesis-updated 2019

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As cardiac IRI is tightly linked to the pro-inflammatory cascades driven by cytokines, neutrophils, and immune signalling, reperfusion-induced release of DAMPs activates pattern recognition receptors, amplifying cytokine production and neutrophil infiltration [27,33]

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For instance, Allobaculum displayed negative correlations with metabolites such as PGP and PC, but was positively correlated with the fatty acid CoA derivative 11Z, 14Z-Eicosadienoyl-CoA

Moreover, an increase in TAC, uric acid, and sulfhydryl content was observed, while the activity of SOD and CAT as well as MDA content remained unmodified