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An increase in the A42/40 ratio, as observed in the intervention group, suggests a potential reversal or slowing of amyloid-beta plaque accumulation, indicating an improvement in disease pathology

Impact of twice-daily budesonide foam administration on early clinical response and endoscopic remission in patients with ulcerative colitis: a post hoc analysis

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The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5

This leads to their clustering and activation, which also induces a conformational change [42,43]

Additional strategies include increasing macrophage expression of iron-export proteins such as ferroportin, or enhancing iron uptake via transferrin receptor modulation