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The disparate conclusions obtained from COX-2 transgenic mice and inhibitors suggest multifaced molecular mechanisms and functions of COX-2 in different cell types and diverse pathological challenges during the progression of NAFLD, which highlights the importance of personalized and cell typespecific drug delivery design according to clinical heterogeneity

(redox cycle)

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We also discuss how pain is influenced by our emotions, stress and memories, and practical tools to control ones psychological perception of pain

A protein truncating HSD17B13 variant and protection from chronic liver disease

Cell Microbiol 15 , 701708 (2013)