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3.2 Regulatory mechanisms of glycolysis and oxidative phosphorylation in astrocytes Astrocytes exhibit a greater glycolytic capacity relative to oxidative phosphorylation, supported by elevated Pfkfb3-driven fructose-2,6-bisphosphate production that accelerates glycolysis, while reduced pyruvate dehydrogenase expression restricts oxidative phosphorylation (Khler et al., 2020)

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