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Active learning driven prioritisation of compounds from on-demand libraries targeting the SARS-CoV-2 main protease

These challenges include ensuring consistent BBB penetration, preventing immunological activation, achieving precise gene silencing, and demonstrating long-term safety

The differences in redox ratios between the tumor and healthy tissues were not substantial

- ceramides - strengthens the hydrolipidic barrier, has a regenerating effect

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Karunakaran S, Diwakar L, Saeed U, Agarwal V, Ramakrishnan S, Iyengar S, Ravindranath V (2007) Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinsons disease: protection by -lipoic acid