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Although both biliverdin and bilirubin are reductants, bilirubin is considered to be the better physiological antioxidant (41)

Funding Statement The author(s) declare that no financial support was received for the research and/or publication of this article

The fluorescence quantum yield (QY) of roGFPs was determined by comparison to Rhodamine 6G (Sigma-Aldrich, www.sigmaaldrich.com) which has a QY of 0.9 when dissolved in water (Magde et al., 2002)