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This DNA is mixed with cellular components, including granules, histones, and cytoplasmic proteins, ultimately leading to the rupture of the plasma membrane and the subsequent release of the NET structure into the extracellular space

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and (3) quiescence, when the rate of fibril growth decreases as monomer depletion occurs (Fig

Crit Care Med 37:28272839 Wacharasint P, Nakada TA, Boyd JH, Russell JA, Walley KR (2012) Normal-range blood lactate concentration in septic shock is prognostic and predictive